What is Nephrotic Syndrome?

Nephrotic Syndrome is a kidney disorder which is characterised by

  • Abnormal protein leak
  • Low levels of proteins in blood (due to protein leakage)
  • Increased levels of lipid
  • The term Nephrotic Syndrome is coined from two words: Nephros (in Greek) meaning kidney and Syndrome denoting a group of symptoms.

    Nephrotic Syndrome is a set of symptoms related to kidney dysfunction, and not a disease, in and of itself. Nephrotic Syndrome is a disorder characterised by loss of proteins in the urine. In realism, Nephrotic Syndrome can be the first sign of various diseases that damage the kidneys, especially tiny blood-filtering units (glomeruli) in the kidneys, where urine is formed. This causes fall in the protein levels in the blood, and water to move into body tissues, causing swelling and bloating of body (edema/Oedema).

Nephrotic Syndrome Diagnosis

  • Signs of a concurrent upper respiratory tract infection may be present and some children have overt evidence of an atopic state with varying degrees of eczema.
  • An occasional child demonstrates evidence of an insect sting and/or bite.
  • Abdominal tenderness will be evident in presence of peritoneal infection.